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The Virtual Journal of Nanotechnology Environment, Health and Safety

A collection of papers addressing diverse aspects of nanotechnology/nanomaterials and risk, co-edited by Jo Anne Shatkin and Warner North, has been published in the November 2010 issue of the journal Risk Analysis, Perspectives on Risks of Nanomaterials and Nanotechnologies: Advancing the Science (Volume 30, Number 11, November 2010). The ten papers address a breadth of topics and offer perspectives on communications, toxicology, risk assessment. Several papers summarize the deliberations of a 2008 workshop on nanotechnology and risk sponsored by the Society for Risk Analysis. Other papers discuss risk governance for nanomaterials and alternative approaches. These papers have been added individually to the Virtual Journal.

The publisher, Wiley Interscience, has graciously made the electronic version of this issue of the journal available to non subscribers for free until July 2011. The Table of Contents for this issue can be accessed at this link:   http://onlinelibrary.wiley.com/doi/10.1111/risk.2010.30.issue-11/issuetoc.

Special Series in Risk Analysis Journal on "Perspectives on Risks of Nanomaterials and Nanotechnologies: Advancing the Science"

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A comprehensive approach to in vitro functional evaluation of Ag/alginate nanocomposite hydrogels
Stojkovska J, Kostic D, Jovanovic Z, Vukasinovic-Sekulic M, Miskovic-Stankovic V, Obradovic B
Carbohydrate Polymers

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The interactions between CdSe quantum dots and yeast Saccharomyces cerevisiae: Adhesion of quantum dots to the cell surface and the protection effect of ZnS shell
Mei J, Yang LY, Lai L, Xu ZQ, Wang C, Zhao J, Jin JC, Jiang FL, Liu Y
Chemosphere

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Physiological and molecular level effects of silver nanoparticles exposure in rice (Oryza sativa L.) seedlings
Nair PMG, Chung IM
Chemosphere

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Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles
Gao F, Yuan Q, Gao L, Cai P, Zhu H, Liu R, Wang Y, Wei Y, Huang G, Liang J, Gao X
Biomaterials

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Exposure to silver nanoparticles induces size- and dose-dependent oxidative stress and cytotoxicity in human colon carcinoma cells
Miethling-Graff R, Rumpker R, Richter M, Verano-Braga T, Kjeldsen F, Brewer J, Hoyland J, Ruban HG, Erdmann H
Toxicology in Vitro

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A Comparative Study of Three Cytotoxicity Test Methods for Nanomaterials Using Sodium Lauryl Sulfate
Kwon JS, Kim KM, Kim KN
Journal of Nanoscience and Nanotechnology

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Biosynthesis of gold nanoparticles using Sargassum swartzii and its cytotoxicity effect on HeLa cells
Dhas TS, Kumar VG, Karthick V, Govindaraju K, Narayana TS
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

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Xanthan gum stabilized gold nanoparticles: Characterization, biocompatibility, stability and cytotoxicity
Pooja D, Panyaram S, Kulhari H, Rachamalla SS, Sistla R
Carbohydrate Polymers

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A spontaneous penetration mechanism of patterned nanoparticles across a biomembrane
Li Y, Zhang X, Cao D
Soft Matter

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Transport across the cell-membrane dictates nanoparticle fate and toxicity: a new paradigm in nanotoxicology
Guarnieri D, Sabella S, Muscetti O, Belli V, Malvindi MA, Fusco S, De Luca E, Pompa PP, Netti PA
Nanoscale

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Zinc oxide nanoparticles, a novel candidate for the treatment of allergic inflammatory diseases
Kim MH, Seo JH, Kim HM, Jeong HJ
European Journal of Pharmacology

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Immunosuppressive and anti-inflammatory properties of engineered nanomaterials
Ilinskaya AN, Dobrovolskaia MA
British Journal of Pharmacology

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The electrokinetic characterization of gold nanoparticles, functionalized with cationic functional groups, and its’ interaction with DNA
Lazarus GG, Revaprasadu N, Lopez-Viota J, Singh M
Colloids and Surfaces B: Biointerfaces

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Coexistence of silver and titanium dioxide nanoparticles: Enhancing or reducing environmental risks?
Zou X, Shi J, Zhang H
Aquatic Toxicology

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Preparation and biological evaluation of photoluminescent carbonaceous nanospheres
Qian J, Chen J, Ruan S, Shen S, He Q, Jiang X, Zhu J, Gao H
Journal of Colloid and Interface Science

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Influence of surface properties of zinc oxide nanoparticles on their cytotoxicity
Altunbek M, Baysal A, Culha M
Colloids and Surfaces B: Biointerfaces

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Safety assessment of engineered metallic nanoparticles in foodstuff
Rainieri S, Olasagasti M, Barranco A
Quality Assurance and Safety of Crops & Foods

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Evaluation of pristine and Eu2O3-added MgB2 ceramics for medical applications: hardness, corrosion resistance, cytotoxicity and antibacterial activity
Batalu D, Stanciuc AM, Moldovan L, Aldica G, Badica P
Materials Science and Engineering: C

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Synthesis of silver nanoparticles from Melia dubia leaf extract and their in vitro anticancer activity
Kathiravan V, Ravi S, Ashokkumar S
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

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Applying accelerator mass spectrometry for low-level detection of complex engineered nanoparticles in biological media
Wang B, Jackson GS, Yokel RA, Grulke EA
Journal of Pharmaceutical and Biomedical Analysis

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Cationic core-shell nanoparticles for intravesical chemotherapy in tumor-induced rat model: Safety and efficacy
Erdogar N, Iskit AB, Eroglu H, Sargon MF, Mungan NA, Bilensoy E
International Journal of Pharmaceutics

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SN38 polymeric nanoparticles: In vitro cytotoxicity and in vivo antitumor efficacy in xenograft balb/c model with breast cancer versus irinotecan
Sepehri N, Rouhani H, Tavassolian F, Monteazeri H, Khoshayand MR, Ghahremani MH, Ostad SN, Atyabi F, Dinarvand R
International Journal of Pharmaceutics

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A biodistribution study of PEGylated PCL-based nanoparticles in C57BL/6 mice bearing B16/F10 melanoma
Lupi M, Colombo C, Frapolli R, Ferrari R, Sitia L, Dragoni L, Bello E, Licandro SA, Falcetta F, Ubezio P, Bigini P, Salmona M, D'Incalci M, Morbidelli M, Moscatelli D
Nanotechnology

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Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury
Esch MB, Mahler GJ, Stokol T, Shuler ML
Lab on a Chip

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Synthesis, characterization and toxicological evaluation of a core-shell copper oxide/polyaniline nanocomposite
de OF Rossetto AL, Vincentini DS, Costa CH, Melegari SP, Matias WG
Chemosphere

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Sunscreens as a Source of Hydrogen Peroxide Production in Coastal Waters
Sanchez-Quiles D, Tovar-Sanchez A
Environmental Science & Technology

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Inhibition of potential uptake pathways for silver nanoparticles in the estuarine snail Peringia ulvae
Khan FR, Misra SK, Bury NR, Smith BD, Rainbow PS, Luoma SN, Valsami-Jones E
Nanotoxicology

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Nano-titanium dioxide bioreactivity with human alveolar type-I-like epithelial cells: Investigating crystalline phase as a critical determinant
Sweeney S, Berhanu D, Ruenraroengsak P, Thorley AJ, Valsami-Jones E, Tetley TD
Nanotoxicology

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Assessing orally bioavailable commercial silver nanoparticle product on human cytochrome P450 enzyme activity
Munger MA, Hadlock G, Stoddard G, Slawson MH, Wilkins DG, Cox N, Rollins D
Nanotoxicology

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Enhanced bioavailability and intestinal uptake of Gemcitabine HCl loaded PLGA nanoparticles after oral delivery
Joshi G, Kumar A, Sawant K
European Journal of Pharmaceutical Sciences

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Uptake of silica nanoparticles: Neurotoxicity and Alzheimer-like pathology in human SK-N-SH and mouse neuro2a neuroblastoma cells
Yang X, He C, Li J, Chen H, Ma Q, Sui X, Tian S, Ying M, Zhang Q, Luo Y, Zhuang Z, Liu J
Toxicology Letters

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Amino acid-dependent transformations of citrate-coated silver nanoparticles: Impact on morphology, stability and toxicity
Shi J, Sun X, Zou X, Zhang H
Toxicology Letters

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Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4
Lozano-Fernandez T, Ballester-Antxordoki L, Perez-Temprano, Rojas E, Sanz D, Iglesias-Gaspar M, Moya S, Gonzales-Fernandez A, Rey M
Nanomedicine: Nanotechnology, Biology and Medicine

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Interaction of Amorphous Silica Nanoparticles with Erythrocytes in Vitro: Role of Oxidative Stress
Nemmar A, Beegam S, Yuvaraju P, Yasin J, Shahin A, Ali BH
Cellular Physiology and Biochemistry

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Nanoparticle toxicity assessment using an in vitro 3-D kidney organoid culture model
Astashkina AI, Jones CF, Thiagarajan G, Kurtzeborn K, Ghandehari H, Brooks BD, Grainger DW
Biomaterials

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In vitro cellular responses to silicon carbide particles manufactured through the Acheson process: Impact of physico-chemical features on pro-inflammatory and pro-oxidative effects
Boudard D, Forest V, Pourchez J, Boumahdi N, Tomatis M, Fubini B, Guilhot B, Cottier M, Grosseau P
Toxicology in Vitro

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Influence of different surfactants on the technological properties and in vivo ocular tolerability of lipid nanoparticles
Leonardi A, Bucolo C, Romano GL, Platania CBM, Drago F, Puglisi G, Pignatello R
International Journal of Pharmaceutics

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PEGylated long circulating nanostructured lipid carriers for Amoitone B: Preparation, cytotoxicity and intracellular uptake
Luan J, Yang X, Chu L, Xi Y, Zhai G
Journal of Colloid and Interface Science

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Chitosan/tripolyphosphate nanoparticles loaded with paraquat herbicide: An environmentally safer alternative for weed control
Grillo R, Pereira AES, Nishisaka CS, de Lima R, Oehlke K, Greiner R, Fraceto LF
Journal of Hazardous Materials

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Spectroscopic investigations, antimicrobial, and cytotoxic activity of green synthesized gold nanoparticles
Lokina S, Suresh R, Giribabu K, Stephen A, Lakshmi Sundaram R, Narayanan V
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

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Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity
Sivaraj R, Rahman PKSM, Rajiv P, Narendhran S, Venckatesh R
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

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Toxic responses in rat embryonic cells to silver nanoparticles and released silver ions as analyzed via gene expression profiles and transmission electron microscopy
Xu L, Shi C, Shao A, Li X, Cheng X, Ding R, Wu G, Chou LL
Nanotoxicology

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Evidence of three-level trophic transfer of quantum dots in an aquatic food chain by using bioimaging
Lee WM, An YJ
Nanotoxicology

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Utility of models of the gastrointestinal tract for assessment of the digestion and absorption of engineered nanomaterials released from food matrices
Lefebvre DE, Venema K, Gombau L, Valerio LG, Raju J, Bondy GS, Bouwmeester H, Singh RP, Clippinger AJ, Collnot EM, Mehta R, Stone V
Nanotoxicology

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Optimising the use of commercial LAL assays for the analysis of endotoxin contamination in metal colloids and metal oxide nanoparticles
Li Y, Italiani P, Casals E, Tran N, Puntes VF, Boraschi D
Nanotoxicology

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Synthesis and Organic Surface Modification of Luminescent, Lanthanide-Doped Core/Shell Nanomaterials (LnF3@SiO2@NH2@Organic Acid) for Potential Bioapplications: Spectroscopic, Structural, and in Vitro Cytotoxicity Evaluation
Runowski M, Ekner-Grzyb A, Mrowczynska L, Balabhadra S, Grzyb T, Paczesny J, Zep A, Lis S
Langmuir

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Topical application of zinc oxide nanoparticles reduces bacterial skin infection in mice and exhibits antibacterial activity by inducing oxidative stress response and cell membrane disintegration in macrophages
Pati R, Mehta RK, Mohanty S, Padhi A, Sengupta M, Vaseeharan B, Goswami C, Sonawane A
Nanomedicine: Nanotechnology, Biology and Medicine

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Resolution of the mediators of in vitro oxidative reactivity in size-segregated fractions that may be masked in the urban PM10 cocktail
Price HD, Jones TP, BeruBe KA
Science of the Total Environment

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A quantitative study of the intracellular concentration of graphene/noble metal nanoparticle composites and their cytotoxicity
Zhou X, Dorn M, Vogt J, Spemann D, Yu W, Mao Z, Estrela-Lopis I, Donath E, Gao C
Nanoscale

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Preparation and evaluation of polyethyleneimine-single walled carbon nanotube conjugates as vectors for pancreatic cancer treatment
Andreoli E, Suzuki R, Orbaek AW, Bhutani MS, Hauge RH, Adams W, Fleming JB, Barron AR
Journal of Materials Chemistry B

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Effects of Nano-MnO2 on Dopaminergic Neurons and the Spatial Learning Capability of Rats
Li T, Shi T, Li X, Zeng S, Yin L, Pu Y
International Journal of Environmental Research and Public Health

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Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity
Walczak AP, Kramer E, Hendriksen PJM, Tromp P, Helsper JPFG, Van der Zande M, Rietjens IMCM, Bouwmeester H
Nanotoxicology

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Toxicity of boehmite nanoparticles: impact of the ultrafine fraction and of the agglomerates size on cytotoxicity and pro-inflammatory response
Forest V, Pailleux M, Pourchez J, Boudard D, Tomatis M, Fubini B, Sennour M, Hochepied JF, Grosseau P, Cottier M
Inhalation Toxicology

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The performance of gradient alloy quantum dots in cell labeling
Soenen SJ, Manshian BB, Himmelreich U, Demeester J, Braeckmans K, De Smedt SC
Biomaterials

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Biodegradable nanoparticles composed of dendrigraft poly-l-lysine for gene delivery
Kodama Y, Nakamura T, Kurosaki T, Egashira K, Mine T, Nakagawa H, Muro T, Kitahara T, Higuchi N, Sasaki H
European Journal of Pharmaceutics and Biopharmaceutics

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Titanium dioxide nanoparticles induce strong oxidative stress and mitochondrial damage in glial cells
Huerta-Garcia E, Perez-Arizti JA, Marquez-Ramirez SG, Delgado-Buenrostro NL, Chirino YI, Iglesias GG, Lopez-Marure R
Free Radical Biology and Medicine

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Docetaxel loaded chitosan nanoparticles: Formulation, characterization and cytotoxicity studies
Jain A, Thakur K, Kush P, Jain UK
International Journal of Biological Macromolecules

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Influence of carbon-based nanomaterials on lux-bioreporter Escherichia coli
Jia K, Marks RS, Ionescu RE
Talanta

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The influence of lysosomal stability of silver nanomaterials on their toxicity to human cells
Setyawati MI, Yuan X, Xie J, Leong DT
Biomaterials

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Filtration and Length Determination of Airborne Carbon Nanotubes in the Submicrometer Range Using Nanofiber Filters
Bahk YK, Wang J
Aerosol and Air Quality Research

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Large scale molecular simulations of nanotoxicity
Jimenez-Cruz CA, Kang SG, Zhou R
Wiley Interdisciplinary Reviews: Systems Biology and Medicine

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Dose ranging, expanded acute toxicity and safety pharmacology studies for intravenously administered functionalized graphene nanoparticle formulations
Kanakia S, Toussaint JD, Chowdhury SM, Tembulkar T, Lee S, Jiang YP, Lin RZ, Shroyer KR, Moore W, Sitharaman B
Biomaterials

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Silver nanoparticles inhibit the gill Na+/K+-ATPase and erythrocyte AChE activities and induce the stress response in adult zebrafish (Danio rerio)
Katuli KK, Massarsky A, Hadadi A, Poumehran Z
Ecotoxicology and Environmental Safety

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An in vitro toxicity evaluation of gold-, PLLA- and PCL-coated silica nanoparticles in neuronal cells for nanoparticle-assisted laser-tissue soldering
Koch F, Moller AM, Frenz M, Pieles U, Kuehni-Boghenbor K, Mevissen M
Toxicology in Vitro

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Effects of size and surface of zinc oxide and aluminum-doped zinc oxide nanoparticles on cell viability inferred by proteomic analyses
Pan CH, Liu WT, Bien MY, Lin IC, Hsiao TC, Ma CM, Lai CH, Chen MC, Chuang KJ, Chuang HC
International Journal of Nanomedicine

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Ecotoxicological Effect of Sublethal Exposure to Zinc Oxide Nanoparticles on Freshwater Snail Biomphalaria alexandrina
Fahmy SR, Abdel-Ghaffar F, Bakry FA, Sayed DA
Archives of Environmental Contamination and Toxicology

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Controlled Synthesis, Optical Properties and Cytotoxicity Studies of CdSe–Poly(lactic acid) Multifunctional Nanocomposites by Ring-Opening Polymerization
Islam MR, Bach LG, Vo TS, Lee DC, Lim KT
Journal of Nanoscience and Nanotechnology

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Toxicity of ZnO Nanoparticles to Macrophages Due to Cell Uptake and Intracellular Release of Zinc Ions
Wang B, Zhang Y, Mao Z, Yu D, Gao C
Journal of Nanoscience and Nanotechnology

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Resveratrol-Loaded Nanoparticles Reduce Oxidative Stress Induced by Radiation or Amyloid- in Transgenic Caenorhabditis elegans
Yin H, Si J, Xu H, Dong J, Zheng D, Lu X, Li X
Journal of Biomedical Nanotechnology

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The effect of protein corona composition on the interaction of carbon nanotubes with human blood platelets
De Paoli SH, Diduch LL, Tegegn TZ, Orecna M, Strader MB, Karnaukhova E, Bonevich JE, Holada K, Simak J
Biomaterials

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The effect of hyperbranched polyglycerol coatings on drug delivery using degradable polymer nanoparticles
Deng Y, Saucier-Sawyer JK, Hoimes CJ, Zhang J, Seo YE, Andrejecsk JW, Saltzman WM
Biomaterials

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Self-reporter shikonin-Act-loaded solid lipid nanoparticle: Formulation, physicochemical characterization and geno/cytotoxicity evaluation
Eskandani M, Nazemiyeh H
European Journal of Pharmaceutical Sciences

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Polylactide-Based Paclitaxel-Loaded Nanoparticles Fabricated by Dispersion Polymerization: Characterization, Evaluation in Cancer Cell Lines, and Preliminary Biodistribution Studies
Adesina SK, Holly A, Kramer-Marek G, Capala J, Akala EO
Journal of Pharmaceutical Sciences

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    This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
    under NSF Award Number EEC-0118007.

     
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