ICON EHS Database Category Explanations
Exposure Pathway
Dermal/Mucous Membrane: material that is absorbed into the body through the skin or mucous system
Inhalation: material that is taken into the body by inhaling
Injection: material that is put into the body using a needle and syringe to pierce the skin
Multiple: material that is taken into the body by two or more of the subcategories within the "Exposure Pathway" category
Oral/Ingestion: material that is taken into the body through the mouth for digestion
Other/Unspecified: material exposure path that is not included in subcategories within the "Exposure Pathway" category or that simply is not specified
Method of Study
Computational and System Modeling: studies that use computer simulations or models to predict hazard effects or physical properties
Environmental Study: studies involving environmental remediation techniques or analysis of the environment - can include theoretical modeling
Ex vivo: studies where either 1) the experiment is performed in vivo and then analyzed in vitro, or 2) part of the subject is removed, the experiment is performed, and the part is returned to the host
In vitro: studies done on tissues or cells outside the living body and in an artificial environment
In vivo: studies done on tissues or cells in the living body of a plant or animal
Material Analysis and Applications: studies that characterize a material to understand its chemical composition and physical properties or that determine how a material is applied in a product formulation
Multiple: studies involving two or more of the subcategories within the "Method of Study" category
Other: studies involving method types not included in the subcategories within the "Method of Study" category
Synthesis: studies that define methods for producing a material
Exposure or Hazard Target
Aquatic Ecosystem: studies where impacts to the aquatic environment are evaluated
Atmospheric Ecosystem: studies where impacts to the air quality are evaluated
Mammalian: studies where mammals are the species targeted
Multiple: studies involving two or more of the subcategories within the "Exposure or Hazard Target" category
Other/Unspecified: studies involving hazard or exposure targets not included in the subcategories within the "Exposure or Hazard Target" given above, or simply not specified
Soil Ecosystem: studies where impacts to the soil quality are evaluated
Risk Exposure Group
Consumer: studies that focus the main exposure risk to the end-of-use consumer where a nanomaterial has been incorporated into a product available on the market
Ecosystem: studies that focus the main exposure risk to a broad range of environmental media, including air and water quality
General Population: studies that focus the main exposure risk to a group of people that are considered to be members of the public at large
Industrial or Research Worker: studies that focus the main exposure risks to a group of people within an industrial, commercial or laboratory setting
Other/Unspecified: studies involving exposure to groups or media other than the subcategories within the "Risk Exposure Group" category given above or simply not specified
Publication Type
Non-peer Reviewed Journal Article: articles that are published in scientific journals but have not been reviewed by experts in the field of study
Other: articles that are not described by any of the subcategories within the "Publication Type" category given above
Peer Reviewed Journal Article: articles that are published in scientific journals and that have been reviewed by experts in that particular field of study and meet the current standards of that field
Public Source: articles that have open and free access typically published in non-scientific journals, newspapers, or websites
Review Article: an article or piece of writing that discusses the author's opinion on an already published work
Target Audience
General Public: articles that are written in more common every-day language for the layman and that tend to explain and clarify scientific principles
Other: articles that are not described by any of the other subcategories within the "Target Audience" category given above
Public Policy: articles that are written for the purpose of steering public policy
Technical Research: articles that are focused at scientific audiences and generally advance scientific knowledge in the field
Content Emphasis
Applications: articles covering studies conducted to demonstrate the usefulness of the material
Commentaries: articles covering studies that explain or summarize prior work
Environmental Fate and Transport: articles covering studies that help define a material's mobility within the environment
Exposure: articles covering studies that help define the likelihood of a test subject coming into contact with the material
Hazard: articles covering studies that help define to what extent a material is toxic or poses a hazard
Policy Reports: articles describing "nano" policy positions of either governmental or non-governmental organizations
Material Production
Both: a material produced intentionally and unintentionally
Engineered: a manmade material produced intentionally
Incidental: a material produced naturally or as an unintentional byproduct of an engineered material or process
Particle Type
Carbon: a nanomaterial consisting of mostly carbon (e.g. carbon nanotubes, buckyballs, fullerenes and carbon black)
Metal: a nanomaterial made from the transition metals on the periodic table (e.g. gold and silver nanoparticles)
Multiple: a nanomaterial consisting of two or more of the subcategories within the "Particle Type" category
Organic/Polymer: a nanomaterial composed of carbon and hydrogen that may also contain any number of other elements such as oxygen, nitrogen, sulfur in single molecule or in long chain form (e.g. polymers, protein, and DNA)
Other/Unspecified: a nanomaterial not included in the subcategories within the "Particle Type" category given above or simply not specified
Oxide: any nanomaterial consisting of oxygen along with any other chemical elements (e.g. Fe3O4 "iron oxide and SiO2 "silica)
Semiconductor: a nanomaterial that contains specialized conducting properties, generally for electronic applications (e.g. Q-dots, CdSe, PbS)
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