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Mesoporous silica nanoparticles in nanotechnology
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Mesoporous silica nanoparticles (MSNs) are a versatile drug delivery system that can be used for loading of different guest molecules such as peptides, proteins, anticancer agents, and genetic material. MSNs are considered promising drug carriers due to their tuneable particle size, pore structure, and surface functionalization. Thus, MSNs provide opportunities for their effective application in a wide variety of fields. In the current review, we discuss both conventional and advanced MSNs synthesis methods, including their applications for drug delivery, gatekeepers, and biosensors. In addition, the research progress in biocompatibility, cytotoxicity, and internalization mechanisms is reported.
In this review, the authors discuss both conventional and advanced mesoporous silica nanoparticles (MSNs) synthesis methods, and in addition, discuss the research progress in biocompatibility, cytotoxicity, and internalization mechanisms.
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Critical Reviews In Biotechnology, 33(3): 229-245 (September 2013)
Critical Reviews in Biotechnology
Douroumis D, Onyesom I, Maniruzzaman M, Mitchell J
Last updated on August 9, 2013
This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.
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