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Title:
Effect of Nanocarbon Sizes on the Cellular Uptake
Date:
2/2013
Link to Journal Abstract
Abstract:
Single-walled carbon nanohorn (CNH) is a type of nanocarbon that is a single-graphene nanometer-sized pseudo tubule with a diameter of 2-5 nm and a length of 40-50 nm. About 2000 CNHs assemble to form a spherical aggregate with a diameter of about 100 nm. CNHs have low toxicity and their potential medical applications have therefore attracted much research attention. In this report, we show that the cellular uptake of CNHs can be controlled by chemical functionalization of the CNH surface and that the controllability can be enhanced by downsizing the CNH aggregates.
Non-technical Summary:
This paper investigates how the cellular uptake of single-walled carbon nanohorns (CNHs) can be controlled by chemical functionalization of the CNH surface and how the controllability can be enhanced by downsizing the CNH aggregates. (Paper in Japanese)
Content Emphasis
Peer Reviewed Journal Article
Exposure Or Hazard Target
Mammalian
Exposure Pathway
Other/Unspecified
Method Of Study
In Vitro
Paper Type
Exposure
Particle Type
Carbon
Production Method
Engineered
Risk Exposure Group
General Population
Target Audience
Technical Research
Citation:
Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan, 2013, 133(2): 151-156
Publication:
Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
Author:
Zhang M, Yudasaka M
Volume:
133
Number:
2
Pages:
151-156
Last updated on February 8, 2013
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This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.
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