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Title: Effects of acid treatment on structure, properties and biocompatibility of carbon nanotubes
Date: 1/2013
  Link to Journal Abstract
Abstract: Carbon nanotubes (CNTs) are promising to be the next generation of viable tools for bioapplications. Further advances in such bioapplications may depend on improved understanding of CNTs physical and chemical properties as well as control over their biocompatibility. Herein we performed a systematic study to show how acid oxidation treatment changes CNTs physical and chemical properties and leads to improved CNTs biocompatibility. Specifically, by incubating CNTs in a strong acid mixture we created a user-defined library of CNTs samples with different characteristics as recorded using Raman energy dispersive X-ray spectroscopy, atomic force microscopy, or solubility tests. Systematically characterized CNTs were subsequently tested for their biocompatibility in relation to human epithelial cells or enzymes. Such selected examples are building pertinent relationships between CNTs biocompatibility and their intrinsic properties by showing that acid oxidation treatment lowers CNTs toxicity providing feasible platforms to be used for biomedical applications or the next generation of biosensors.
Non-technical Summary: In this paper, the authors performed a systematic study to show how acid oxidation treatment changes carbon nanotubes (CNTs) physical and chemical properties and leads to improved CNTs biocompatibility. CNTs were subsequently tested for their biocompatibility in relation to human epithelial cells or enzymes.
Exposure Or Hazard Target Mammalian
Exposure Pathway Other/Unspecified
Method Of Study In Vitro
Paper Type Hazard
Particle Type Carbon
Production Method Engineered
Risk Exposure Group General Population
Citation: Applied Surface Science, 264: 261-268 (January 2013)
Publication: Applied Surface Science
Author: Dong C, Campell AS, Eldawud R, Perhinschi G, Rojanasaku Y, Dinu CZ
Volume: 264
Pages: 261-268
     


Last updated on January 22, 2013
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This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.

 		 
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