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Title: Activity of Antimicrobial Silver Polystyrene Nanocomposites
Date: 10/2012
  Link to Journal Abstract
Abstract: A simple technique based on doping polymers with in situ generated silver nanoparticles (Ag/PS films) has been developed. In particular, an antiseptic material has been prepared by dissolving silver 1,5-cyclooctadiene-hexafluoroacetylacetonate in amorphous polystyrene, and the obtained solid solution has been heated for ca. 10 s at a convenient temperature (180°C). Under such conditions the metal precursor decomposes producing silver atoms that diffuse into the polymer and clusterize. The antimicrobial characteristics of the resulting polystyrene-based material have been accurately evaluated toward Escherichia coli (E. coli) comparing the cytotoxicity effect of 10 wt.% and 30 wt.% (drastic and mild annealing) silver-doped polystyrene to the corresponding pure micrometric silver powder. Two different bacterial viability assays were performed in order to demonstrate the cytotoxic effect of Ag/PS films on cultured E. coli: (1) turbidimetric determination of optical density; (2) BacLight fluorescence-based test. Both methods have shown that silver-doped polystyrene (30 wt.%) provides higher antibacterial activity than pure Ag powder, under similar concentration and incubation conditions.
Non-technical Summary: A simple technique based on doping polymers with in situ generated silver nanoparticles (Ag/PS films) has been developed. The antimicrobial characteristics of the resulting polystyrene-based material have been accurately evaluated toward Escherichia coli (E. coli) comparing the cytotoxicity effect of 10 wt.% and 30 wt.% silver-doped polystyrene to the corresponding pure micrometric silver powder.
Content Emphasis Peer Reviewed Journal Article
Exposure Or Hazard Target Other/Unspecified
Exposure Pathway Other/Unspecified
Method Of Study Material Analysis and Applications
Paper Type Hazard
Particle Type Metal
Production Method Engineered
Risk Exposure Group Other/Unspecified
Target Audience Technical Research
Citation: Journal of Nanomaterials, 2012, Article ID 185029 (7 pp)
Publication: Journal of Nanomaterials
Author: Palomba M, Carotenuto G, Cristino L, Di Grazia MA, Nicolais F, De Nicola S
Volume: 2012
Number: Article ID 185029
Pages: (7 pp)
     


Last updated on January 18, 2013
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This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.

 		 
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