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Title:

Toxicity Assessment of Iron Oxide Nanoparticles in Zebrafish (Danio rerio) Early Life Stages

Date:

9/2012

Link to Journal Abstract

Abstract:

Iron oxide nanoparticles have been explored recently for their beneficial applications in many biomedical areas, in environmental remediation, and in various industrial applications. However, potential risks have also been identified with the release of nanoparticles into the environment. To study the ecological effects of iron oxide nanoparticles on aquatic organisms, we used early life stages of the zebrafish (Danio rerio) to examine such effects on embryonic development in this species. The results showed that ?10 mg/L of iron oxide nanoparticles instigated developmental toxicity in these embryos, causing mortality, hatching delay, and malformation. Moreover, an early life stage test using zebrafish embryos/larvae is also discussed and recommended in this study as an effective protocol for assessing the potential toxicity of nanoparticles. This study is one of the first on developmental toxicity in fish caused by iron oxide nanoparticles in aquatic environments. The results will contribute to the current understanding of the potential ecotoxicological effects of nanoparticles and support the sustainable development of nanotechnology.

Non-technical Summary:

To study the ecological effects of iron oxide nanoparticles on aquatic organisms, the authors used early life stages of the zebrafish (Danio rerio) to examine such effects on embryonic development in this species. An early life stage test using zebrafish embryos/larvae is also discussed and recommended in this study as an effective protocol for assessing the potential toxicity of nanoparticles.

Content Emphasis

Peer Reviewed Journal Article

Exposure Or Hazard Target

Aquatic Ecosystem

Exposure Pathway

Other/Unspecified

Method Of Study

Material Analysis and Applications

Environmental Study

Paper Type

Environmental Fate and Transport

Particle Type