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Title: Plasmid-Templated Shape Control of Condensed DNA–Block Copolymer Nanoparticles
Date: 10/2012
  Link to Journal Abstract
Abstract: DNA-containing micellar nanoparticles with distinctly different and highly uniform morphologies are prepared via condensation of plasmid DNA with a block copolymer of polyethylene glycol and a polycation in solvents of different polarity. Molecular dynamics simulations explain the underlying mechanism.
Non-technical Summary: In this study, DNA-containing micellar nanoparticles with distinctly different and highly uniform morphologies are prepared via condensation of plasmid DNA with a block copolymer of polyethylene glycol and a polycation in solvents of different polarity. Molecular dynamics simulations explain the underlying mechanism.
Content Emphasis Peer Reviewed Journal Article
Exposure Or Hazard Target Mammalian
Exposure Pathway Other/Unspecified
Method Of Study Material Analysis and Applications
Paper Type Applications
Particle Type Other/Unspecified
Production Method Engineered
Risk Exposure Group General Population
Target Audience Technical Research
Citation: Advanced Materials, 2013, 25(2): 227-232
Publication: Advanced Materials
Author: Jiang X, Qu W, Pan D, Ren Y, Williford JM, Cui H, Luijten E, Mao HQ
Volume: 25
Number: 2
Pages: 227-232
     


Last updated on February 1, 2013
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This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.

 		 
Rice University