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The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems
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An understanding of the interactions between nanoparticles and biological systems is of significant interest. Studies aimed at correlating the properties of nanomaterials such as size, shape, chemical functionality, surface charge, and composition with biomolecular signaling, biological kinetics, transportation, and toxicity in both cell culture and animal experiments are under way. These fundamental studies will provide a foundation for engineering the next generation of nanoscale devices. Here, we provide rationales for these studies, review the current progress in studies of the interactions of nanomaterials with biological systems, and provide a perspective on the long-term implications of these findings.
In this paper, the authors review the current progress in studies of the interactions of nanomaterials with biological systems, and provide a perspective on the long-term implications of the findings from such studies.
Peer Reviewed Journal Article
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Annual Review of Biomedical Engineering, 14: 1-16 (August 2012)
Annual Review of Biomedical Engineering
Albanese A, Tang PS, Chan WCW
Last updated on September 25, 2012
This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.
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