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Green Synthesis of Curcumin Capped Gold Nanoparticles and Evaluation of Their Cytotoxicity
Link to Journal Abstract
A green approach to synthesize gold nanoparticles using turmeric rhizome extract, curcumin and curcumin glycoside acting as reducing and stabilizing agents at room temperature is described. The obtained gold nanoparticles were characterized by UV-Vis spectroscopy, transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FTIR). The possible mechanism for the stabilization of nanoparticles is due to the chelation of metal with 1,3-diketone functionality of the curcumin. The gold nanoparticle curcumin hybrids show long term colloidal stability. Furthermore we evaluate the cytotoxic behaviour of curcumin glycoside-Au nanoparticles.
This paper describes a green approach to synthesize gold nanoparticles using turmeric rhizome extract, curcumin and curcumin glycoside acting as reducing and stabilizing agents at room temperature. The authors also evaluate the cytotoxic behaviour of the curcumin glycoside-Au nanoparticles.
Peer Reviewed Journal Article
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Nanoscience and Nanotechnology Letters, 5(12): 1258-1265 (December 2013)
Nanoscience and Nanotechnology Letters
Sreelakshmi C, Goel N, Datta KKR, Addlagatta A, Ummanni R, Reddy BVS
Last updated on January 24, 2014
This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.
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