ICON Web & News
Search Using OECD Database
Return to Previous Page
Addition or Correction
The toxicity of Gold Nanoparticles in relation to their physiochemical properties
Link to Journal Paper
The rapid emergence of gold nanoparticles (AuNPs) technology holds great promise for future applications due to their large volume specific surface areas with high diverse surface activities than bulk gold. These properties have made AuNPs of great importance in the development of excellent nanoelectronic chips, promising vehicle for a wide range of biomedical and environmental applications. However, the huge impact arising from the physiochemical properties has given rise to new concerns for future health status. Currently, there is dearth information on AuNPs health effects and no regulatory safety and guidelines relating their properties to toxicities. This review, therefore, focuses on the potential toxicological aspect of AuNPs experienced so far and their interactions with biological systems. These can be applied as measures to improve their biomedical applications and risk assessment. However, assessing the safety issues of nanoparticles is quite challenging, because of the vast physiochemical properties that confound their biomedical and toxicological profiles. Therefore more research with standardized NPs physicochemical properties is needed based on the different types of AuNPs to establish both in vitro and in vivo nanotoxicities. The establishment of each size with specific ligand properties will update the complex conflicting ideas emanating from the different AuNPs safety studies thereof.
This review focuses on the potential toxicological aspect of gold nanoparticles (AuNPs) experienced so far and their interactions with biological systems. More research with standardized NPs physicochemical properties is needed based on the different types of AuNPs to establish both in vitro and in vivo nanotoxicities.
Exposure Or Hazard Target
Method Of Study
Risk Exposure Group
Biomedical Research, 2013, 24(3): 400-413
Biomedical Research - India
Last updated on September 20, 2013
This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.
Why Join Us?
Mission and Strategy
Good Nano Guide
Nano EHS Research Needs
Current Practices Survey