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Evaluate the potential toxicity of quantum dots on bacterial metabolism by microcalorimetry
Link to Journal Abstract
Herein, we evaluated the toxic effects of mercaptoacetic acid (MAA)-CdSe quantum dots (QDs), MAA-CdSe/ZnS QDs and cysteamine (CA)-CdSe/ZnS QDs on the growth of both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) by microcalorimetry. Thermogenic curves of bacteria were recorded and bioeffects of QDs on bacteria were investigated. The results suggested that both MAA-CdSe QDs and MAA-CdSe/ZnS QDs inhibited the E. coli growth but stimulated the S. aureus growth with dose-dependent type. The inhibition or stimulation efficiency of QDs on E. coli or S. aureus growth all decreased dramatically after UV irradiation, which was due to the liberation of more toxic Cd2+. In addition, MAA-CdSe/ZnS QDs and CA-CdSe/ZnS QDs affected the growth of E. coli and S. aureus differently. MAA-CdSe/ZnS QDs could not affect the growth of bacteria, while CA-CdSe/ZnS QDs inhibited the bacterial growth dramatically, which resulted from the negative charge on the surface of these bacteria.
In this study, the authors evaluated the toxic effects of mercaptoacetic acid (MAA)-CdSe quantum dots (QDs), MAA-CdSe/ZnS QDs and cysteamine (CA)-CdSe/ZnS QDs on the growth of both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) by microcalorimetry. Thermogenic curves of bacteria were recorded and bioeffects of QDs on bacteria were investigated.
Peer Reviewed Journal Article
Exposure Or Hazard Target
Method Of Study
Environmental Fate and Transport
Risk Exposure Group
Thermochimica Acta, 552: 98-105 (January 2013)
Xiao Q, Huang S, Su W, Li P, Liu Y
Last updated on March 20, 2013
This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.
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