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Title: Supramolecular reactive sulphur nanoparticles: a novel and efficient antimicrobial agent
Date: 1/2013
  Link to Journal Abstract
Abstract: Antimicrobial resistance continues to be an inexorable threat for the biomedical and biochemical researchers. Despite the novel discoveries in drug designing and delivery, high-throughput screening and surveillance data render the prospects for new antimicrobial agents as bleak as ever. The advent of nanotechnology, however, strengthens pharmacology by offering effective therapeutics to treat this aforementioned problem. Several nanoparticles of the known elements have already been reported for their antimicrobial efficacy. Nanosized fabrication of elemental sulphur with suitable surface modifications offers to retrieve the use of sulphur (man's oldest known ecofriendly microbicide) as a potential antimicrobial agent. Sulphur nanoparticles (SNPs) are effective against both conventionally sulphur-resistant and sulphur-susceptible microbes (fungi and bacteria). Moreover, biocompatible polymers present on the surface of SNPs minimize toxicity during application. Here, we focus on various aspects of physicochemical features of SNPs and their biochemical interactions with microbes. The present review also illustrates the effects of SNPs on plants and animals in terms of cytotoxicity and biocompatibility.
Non-technical Summary: This review focuses on various aspects of physicochemical features of sulphur nanoparticles (SNPs) and their biochemical interactions with microbes. The review also illustrates the effects of SNPs on plants and animals in terms of cytotoxicity and biocompatibility.
Content Emphasis Peer Reviewed Journal Article
Exposure Or Hazard Target Multiple
Exposure Pathway Other/Unspecified
Method Of Study Other
Paper Type Environmental Fate and Transport
Particle Type Other/Unspecified
Production Method Engineered
Risk Exposure Group Ecosystem
Target Audience Technical Research
Citation: Journal of Applied Microbiology, 114(1): 1-10 (January 2013)
Publication: Journal of Applied Microbiology
Author: Choudhury SR, Goswami A
Volume: 114
Number: 1
Pages: 1-10
     


Last updated on January 22, 2013
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This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.

 		 
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