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Title:
Physiological behavior of quantum dots
Date:
12/2012
Link to Journal Abstract
Abstract:
Quantum dots (QDs) have shown great potentials in biomedical applications like bioimaging, sensors and diagnostics due to various advantages such as their robust fluorescence, remarkable photostability, large absorption cross section, and tunable fluorescence emission. The fate, behavior, metabolism, and toxicities of QDs are the primary aspects to be assessed before their bio-applications. Numerous studies concerning those aspects have been reported in the past years. However, only several reviews discussed the toxicities of QDs and various contradictory conclusions appear between these studies. In this review, the fate, metabolism, and behaviors of various QDs and crucial parameters that may determine their fate and behavior in vivo are discussed in depth. This review may provide insights for a better understanding of the biological impacts of QDs. We also propose several suggestions for how to develop QDs application in humans in the future.
Non-technical Summary:
In this review, the fate, metabolism, and behaviors of various QDs and crucial parameters that may determine their fate and behavior in vivo are discussed in depth. This review may provide insights for a better understanding of the biological impacts of QDs. The authors also propose several suggestions for how to develop QDs application in humans in the future.
Content Emphasis
Review Article
Exposure Or Hazard Target
Mammalian
Exposure Pathway
Other/Unspecified
Method Of Study
Multiple
Paper Type
Hazard
Particle Type
Semiconductor
Production Method
Engineered
Risk Exposure Group
General Population
Target Audience
Technical Research
Citation:
WIREs Nanomedicine and Nanobiotechnology, 4(6): 620-637 (November/December 2012)
Publication:
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
Author:
Xu L, Chen C
Volume:
4
Number:
6
Pages:
620-637
Last updated on December 7, 2012
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This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.
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