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Carbon Nanoparticle Toxicity to marine algae Navicula longa and Isochrysis galbana
Link to Journal Abstract
Present study reports cytotoxicity of Carbon Nanoparticles to Navicula and Isochrysis. Cytotoxicity was determined by morphological changes, cell density count, Acid Phosphatase and Lactate dehydrogenase assays. Carbon nanoparticles (CNPs) promote concentration as well as exposure dependent toxicity to Navicula & Isochrysis, which exhibited cell death, necrotic changes such as cell shrinkage and pycnosis of nucleus. Lactate Dehydrogenase (LDH) & Acid Phosphatase (ACP) activities elevated significantly, in both algae, in a dose and exposure dependant manner. In Navicula and Isochrysis, LDH activity was elevated by 42.3% and 60.7%, and 44.5% and 90.3%, on exposure to 0.05 mg/mL and 1 mg/mL CNPs for 10 days respectively. Similarly, ACP activity in both Navicula and Isochrysis was elevated by 34.6% and 55.4%, and 11.7% and 18.5%, on exposure to 0.05 mg/mL and 1 mg/mL of CNPs for 10 days respectively, as compared to the controls. The occurrence of tube like structures under the influence of CNPs in algae was also observed.
For this study, the cytotoxicity of Carbon Nanoparticles to Navicula and Isochrysis. Cytotoxicity was determined by morphological changes, cell density count, Acid Phosphatase and Lactate dehydrogenase assays.
Peer Reviewed Journal Article
Exposure Or Hazard Target
Method Of Study
Environmental Fate and Transport
Risk Exposure Group
Indian Journal of Geo-Marine Sciences, 41(4): 331-337 (August 2012)
Indian Journal of Geo-Marine Sciences
Miranda AA, Shaikh SM, Sarode PR, Desai PV
Last updated on December 5, 2012
This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.
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