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Title: Differential Oxidative Stress of Octahedral and Cubic Cu2O Micro/Nanocrystals to Daphnia magna
Date: 9/2012
  Link to Journal Abstract
Abstract: This study attempts to understand the impact of different shapes of an individual micro/nanomaterial on their biotoxicities to aquatic organisms. Two differently shaped Cu2O micro/nanocrystals (cubes and octahedrons with side lengths of 900 nm) were exposed to Daphnia magna for 72 h, afterward several antioxidant biomarkers such as reactive oxygen species (ROS), catalase (CAT), total antioxidant capacity (T-AOC), and malondialdehyde (MDA) in D. magna were measured. We demonstrated the differential influences of two crystallographic Cu2O nanocrystals on the antioxidant process. Specifically, octahedral Cu2O nanocrystals showed a higher level of oxidative stress, possibly because of its larger surface area and higher reaction activity of the octahedron. The biomarker results further showed that the oxidative stress and antioxidant mechanism process involved three stages—antioxidant response, oxidation inhibition, and antioxidant inactivation. Furthermore, the accumulation of MDA was mainly responsible for the ROS-induced toxicity.
Non-technical Summary: This study attempts to understand the impact of different shapes of an individual micro/nanomaterial on their biotoxicities to aquatic organisms. Two differently shaped Cu2O micro/nanocrystals (cubes and octahedrons with side lengths of 900 nm) were exposed to Daphnia magna for 72 h, and afterward several antioxidant biomarkers such as reactive oxygen species (ROS), catalase (CAT), total antioxidant capacity (T-AOC), and malondialdehyde (MDA) in D. magna were measured.
Content Emphasis Peer Reviewed Journal Article
Exposure Or Hazard Target Aquatic Ecosystem
Exposure Pathway Other/Unspecified
Method Of Study Environmental Study
Paper Type Environmental Fate and Transport
Particle Type Oxide
Production Method Engineered
Risk Exposure Group Ecosystem
Target Audience Technical Research
Citation: Environ. Sci. Technol., 2012, 46(18): 10255-10262
Publication: Environmental Science & Technology
Author: Fan W, Wang X, Cui M, Zhang D, Zhang Y, Yu T, Guo L
Volume: 46
Number: 18
Pages: 10255-10262
     


Last updated on October 15, 2012
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This work is supported in part by the Nanoscale Science and Engineering Initiative of the National Science Foundation
under NSF Award Number EEC-0118007.

 		 
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